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Taking statins , a type of cholesterin - frown drug , may reduce the risk of line of descent clot in people who take hormone therapy for menopause .
Hormone therapycan let off the symptoms of the transition into menopause , call perimenopause , as well as symptoms that persist after menopause . During perimenopause , catamenial periods become less frequent and hormone levels drop , which can trigger off raging flashes , night sweat and vaginal dryness . Hormone therapy can assuage these symptom by essentially replacing the lost internal secretion .
Hormone therapy can help relieve symptoms that emerge during the transition into menopause and shortly after menopause.
However , some of these treatments — most notably , endocrine pills remove by rima oris — raise the peril of venous thromboembolism ( VTE ) , in which blood line clot organize inside veins .
But a young report , published Friday ( Dec. 15 ) in the journalJAMA connection Open , suggest that women who take internal secretion therapy and statins together face a significantly lower hazard of VTE than their peers who take only hormone therapy . Higher doses of statins came with greater reductions in risk .
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" We base statin therapy was associated with reduced , but not eliminated , risk of VTE colligate with exogenous hormones , " the discipline source wrote in the story . These findings paint a picture that statins could improve the safety of these therapy for patients concerned in taking them .
That said , the research was base on a recapitulation of insurance claim , rather than on a gold - standard clinical trial , so it can not show that statins labor the decline in VTE risk . Future trials should confirm this tie , the authors wrote .
The study include data point from woman ages 50 to 64 years who filed commercial-grade insurance claims in the U.S. between 2008 and 2019 . Perimenopause mostoften get between eld 45 and 55and can last years , with symptom sometimes lollygag after menopause .
Among the char , the researchers identify about 20,000 who had a new VTE diagnosis in the subject ’s prison term bod . They then identified a group of more than 200,000 woman without VTE , to serve as a point of comparability . Among all the women , they identified who had a prescription drug for hormone therapy , statins or both .
People take both hormone therapy and statins still faced a high risk of VTE compared with people drive neither medication . However , their risk of infection was downhearted than that of people taking only endocrine therapy — they had a 25 % increase endangerment rather than a 51 % increase risk .
People who took " high - intensity statins , " the most potent at lowering cholesterin , saw the most welfare .
While the subject area does indicate that statins could thin the hormone - therapy - related peril of blood clots , it has several limitation . For example , the insurance policy datum offer only a fond aesculapian history of each patient role , so each person ’s peril of VTE could n’t be full flesh out . It also lacked information on the enjoyment of over - the - counter drugs , like Bayer , which may strike the risk of VTE .
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The study also chunk together people who take on oral internal secretion therapy with those who used non - unwritten options , such as patches , spray and vaginal rings . Historically , VTE endangerment has been tied to hormone pills , while the other choice likely come with a far lower or negligible risk of these blood clots , according to the American College of Obstetricians and Gynecologists .
This article is for informational purposes only and is not mean to put up aesculapian advice .
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