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Do laboratory crumb have the power to imagine , like human being do ? A new study says yes .

Rats may be able of a case of imagination that ’s crucial for route planning , research from the Howard Hughes Medical Institute ( HHMI ) paint a picture . Although the creative arts spring to mind when we retrieve of imagination , the power also plays function in everyday tasks , like navigating our environs . People always imagine the itinerary they will take to get to home , whether it ’s a routine commute to work or a misstep to an unfamiliar emplacement .

photo shows a rat in the center of an area with images projected on its walls. The rat is hooked up to an apparatus that�s suspended above its head

Scientists tested rats' ability to imagine using virtual reality and a brain-machine interface that reads brain activity.

This type of imagination is controlled by thehippocampus , a brain region involved inlearning and memory . People with a damaged hippocampus conflict to imagine scenario , include future path , co - lead study authorChongxi Lai , a research specializer at HHMI ’s Janelia Research Campus in Virginia , told Live Science . Until now , scientist could n’t determine whether other creature , such asrats , possess this form of imagination .

In the study , published Thursday ( Nov. 2 ) in the journalScience , the researchers used practical reality ( VR ) and a brain - auto interface to show that rats have this capability .

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an illustration of the brain with a map superimposed on it

The field of study is provocative because it challenge the long - held assumption that rats might not be up to of thinking beyond their straightaway circumstances , saidKenneth Kay , a neuroscientist at Columbia University ’s Zuckerman Institute who was not involved with the work .

The squad implanted electrodes into the rats ' encephalon to measure their hippocampal action . They then immersed them in a VR world by order them in an arena surrounded by a 360 - degree screen that displayed a practical environment . The rats were commit on a spherical treadmill that allowed them to rotate freely and view the integral aspect .

The researchers then civilise the bum to run toward a virtual goalpost to receive a delicacy . The treadmill ’s motility updated the rat ’s position in the practical surroundings . After several beat , each with the same goalpost at a random location , the rat had research the whole landscape painting .

A reconstruction of neurons in the brain in rainbow colors

For each set of coordinate in the practical environment , the electrodes detected a specific pattern of activity in the genus Hippocampus . The team speculate that rats could recreate those patterns if they imagined conform to a route along those coordinate , rather than in reality launch the route .

The researchers disconnected the treadmill and rewarded the so-and-so for reproducing the hippocampal activity figure associated with a goal location . In this " Jumper "   job — named after a 2008 pic of the same name — the mentality - machine interface translate the animal ’s mastermind activity into apparent motion on the practical realness CRT screen . Essentially , the animal apply its thoughts to navigate to the payoff by first consider about where they involve to go to get the reward . ( television acknowledgment : Chongxi Lai )

So , they set up a game where rats only had tothinkabout moving toward a goalpost ; the practical environs jump to co-ordinate free-base on the electrode readings instead of treadmill movements . Named after a 2008 movie about teleportation , this " Jumper " secret plan showed that rats planned efficient routes to the goalpost without wander and regardless of how they physically moved .

Robot and young woman face to face.

Lastly , the researchers tested whether the rats could imagine moving an object toward the goalpost , rather than themselves .

Nicknamed the " Jedi " biz , this required the rat to " use the Force " to move a virtual box toward the goalpost . The rodents ' success show that they could tackle their genial map to think about navigating an object through their environment , without move themselves .

In the 2d task , the " Jedi " task — a nod to Star Wars — the rat move an aim to a location by thoughts alone . The rat is fixed in a virtual place but " moves " an object to a goal in the VR space by controlling its hippocampal activity , like how a person sitting in their office might imagine taking a cup next to the coffee machine and fill it with coffee . The researchers then changed the location of the goal , requiring the fauna to produce activity pattern associated with the new positioning . ( Video cite : Chongxi Lai )

an edited photo of a white lab mouse against a pink and blue gradient background

Lai mention that scientist already knew about patterns of hippocampal action that correspond to environmental locations inhumansandrats . " But it has n’t been shown that animals can keep in line it " until now .

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interchangeable to humans , the rats took only a few seconds to plan path , suggest this shape of imagery may be similar between these species . " I could see the same experimentation being go in human subject and producing similar answer , which by itself gets at the potential law of similarity , " Kay said .

Senior subject field authorAlbert Leesaid he would like to research whether rats can imagine voyage an surroundings without get cue , as well as probe how other brain regions communicate with the hippocampus during resource to " get a whole picture of the underlie processes for this very mellow - layer cognitive function . "

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